Autoimmune Diseases Surprisingly Similar to Celiac Disease

Discoveries made in researching celiac diseasegluten, we don't yet understand what triggers this
have created new possibilities of understanding forattack. Over time, these attacks on the nervous
other autoimmune diseases. These include somesystem wear down the fatty myelin sheaths
common, frustrating diseases and you havesurrounding axons for the spinal cord and brain.
probably known someone suffering from one ofMS usually manifests itself in young adulthood and
them. Celiac disease sufferers share some innateafflicts women more often than men.
traits with sufferers of type 1 diabetes, multipleRheumatoid Arthritis
sclerosis and rheumatoid arthritis.Rheumatoid arthritis appears to be like CD in that
Researchers currently believe people with thesepeople with specific genes seem to have an
diseases have three things in common that mayimmune response that causes inflammation of
lead to their respective conditions: a geneticvarious tissues, especially synovial joints.
predisposition for a heightened immune reactivity,While we still don't know the exact trigger for
a leaky gut, and probably some external triggerrheumatoid arthritis, we have more ideas than we
that passes through their leaky gut into theirdo for type 1 diabetes or multiple sclerosis. For
highly reactive immune system.example, cigarette smoking and hormonal changes
One key difference, however, is that in celiacappears to have a statistically significant effect on
disease we know with some certainty what thatthe occurrence of rheumatoid arthritis. Currently,
external trigger is: gluten and its close cousins.some improvement of RA seems to occur with
Researchers aren't yet confident they understandhormonal therapies, particularly in women near
the trigger for these other conditions.menopause.
Type 1 DiabetesWhere Do We Go From Here?
Type 1 diabetes, more clinically called DiabetesSince scientists and researchers have only
mellitus type 1 or colloquially referred to asrecently developed their hypothesis of the
juvenile diabetes, occurs when an individual'spermeable intestine (leaky gut) being related to
immune system attacks beta cells responsible foreach of these autoimmune diseases, we don't yet
creating insulin in the pancreas. This increasesknow what will come of this understanding. But
insulin in their urine and blood.the hope is that by eliminating one of the three
So when in celiac disease antibodies attack the villifactors associating these diseases and leading to
along the intestinal wall, in type 1 diabetesautoimmunity (the body essentially attacking
antibodies attack a key functionality of theitself), namely the heightened immune reactivity,
pancreas.the leaky gut or the external trigger, they might
Diabetes mellitus type 1 can be fatal if leftbe able to curb and even eliminate the symptoms
untreated.of the fundamental disease.
Multiple SclerosisCeliac disease provides some hope in this regard
In multiple sclerosis (MS), clinically known asbecause when we eliminate the external trigger -
disseminated sclerosis, the immune systemgluten - we mostly eliminate the symptoms and
attacks the nervous system. Unlike with CD andeffects of the disease.